Patrick Arnold
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Patrick Arnold (born 1966) is an American
organic chemist Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J. ...
known for introducing androstenedione, 1-androstenediol, and
methylhexanamine Methylhexanamine (also known as methylhexamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA; trade names Forthane and Geranamine) is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed a ...
into the dietary supplement market, and for creating the designer steroid
tetrahydrogestrinone Tetrahydrogestrinone (THG), known by the nickname The Clear, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It was developed by Patrick Arnold and was used by a number of high-profile ...
, also known as THG and "the clear".Creator Of 'The Clear' Imprisoned
CBS News, 04 Aug 2006, retrieved July 2007
THG, along with two other anabolic steroids that Arnold manufactured ( norbolethone and
desoxymethyltestosterone Desoxymethyltestosterone (DMT), known by the nicknames Madol and Pheraplex, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-methylated derivative of dihydrotestosterone (DHT) which was never marketed for medical u ...
(DMT)), not banned at the time of their creation, were hard-to-detect drugs at the heart of the
BALCO The Bay Area Laboratory Co-operative (BALCO) (1984–2003) was an American company led by founder and owner Victor Conte. In 2003, journalists Lance Williams and Mark Fainaru-Wada investigated the company's role in a drug sports scandal later re ...
professional sports doping scandal. BALCO distributed these worldwide to world-class athletes in a wide variety of sports ranging from track and field to professional baseball and football. Patrick Arnold also reintroduced
methylhexanamine Methylhexanamine (also known as methylhexamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA; trade names Forthane and Geranamine) is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed a ...
into the market as a dietary supplement under the mark Geranamine, a substance that has gained popularity. Arnold, who is also an amateur bodybuilder, initially gained notoriety as "the Father of Prohormones."Henry K. Lee (August 4, 2006
Inventor of 'clear' steroid gets 3 months in prison
The
San Francisco Chronicle The ''San Francisco Chronicle'' is a newspaper serving primarily the San Francisco Bay Area of Northern California. It was founded in 1865 as ''The Daily Dramatic Chronicle'' by teenage brothers Charles de Young and Michael H. de Young. The ...


Life and early career

Arnold grew up in Guilford, Connecticut. At age 11 he started working out after his father gave him a set of weights. During the late 1970s and early 1980s, despite following protein diets, he grew frustrated with his inability to put on much muscle mass. According to his version of events, Arnold's first contact with steroids happened when "a guy in a gym got him a cheap counterfeit steroid that contained just enough
methyltestosterone Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low ...
that it added 10 pounds of muscle in all the right places." This sparked his interest in chemistry, and in 1990 Arnold graduated with a bachelor's degree in chemistry from the University of New Haven.George Dohrmann (October 09, 2006
Is This Dr. Evil? A legend in the sports netherworld, chemist Patrick Arnold--inventor of THG--breaks his silence on his role in the BALCO scandal and hints of a future filled with scary science
,
Sports Illustrated ''Sports Illustrated'' (''SI'') is an American sports magazine first published in August 1954. Founded by Stuart Scheftel, it was the first magazine with circulation over one million to win the National Magazine Award for General Excellence twi ...
After graduation Arnold took a lab job in New Jersey that allowed him enough free time to research performance enhancers. He also took classes on organic synthesis at the
University of Connecticut The University of Connecticut (UConn) is a public land-grant research university in Storrs, Connecticut, a village in the town of Mansfield. The primary 4,400-acre (17.8 km2) campus is in Storrs, approximately a half hour's drive from H ...
and Montclair State, and "devoured" books on supplements and steroids, studying both approved and unapproved Western drugs and those used by the East Germans in their doping heyday. In 1996 he befriended Dan Duchaine, who introduced Arnold to Stan Antosh, the owner of Osmo Therapy, a supplement company then based in San Francisco. Antosh persuaded Arnold to move his research to a small company in
Seymour, Illinois Seymour is a census-designated place in Champaign County, Illinois, United States. At the 2020 census it had a population of 317. It is part of Mahomet-Seymour Community Unit School District No. 3. Geography Seymour is located at (40.1069769, - ...
, called Bar North America, which was owned by Ramlakhan Boodram. In Seymour, Arnold reviewed old patents looking for drugs that had never made it to market or were used only briefly. Later that year he introduced androstenedione to the North American market, which became successful after
Mark McGwire Mark David McGwire (born October 1, 1963), nicknamed "Big Mac", is an American former professional baseball first baseman who played 16 seasons in Major League Baseball (MLB) from 1986 to 2001 for the Oakland Athletics and the St. Louis Card ...
was found using it. But because their company didn't sell andro directly to consumers — but only as an ingredient to other supplement makers — Arnold missed out on a financial windfall. In 2001 Arnold's company introduced the prohormone 1-Androstenediol, under the marketing name 1-AD. Like andro, 1-AD is a prohormone that is easily converted by the body into 1-testosterone, and it sold well. But the boom was short-lived. In January '05 an amendment to the federal
Controlled Substance Act The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated. It was passed by the 91st United States ...
banned prohormones. The company lost 60% of their sales, and became unprofitable. According to Arnold,
Victor Conte Victor Conte Jr. (born 1950 in Fresno, California) is a former bassist with Tower of Power and the founder and president of Bay Area Laboratory Co-operative (BALCO), a sports nutrition center in California. He served time in prison in 2005 after p ...
contacted him in 2000 seeking undetectable drugs. Arnold offered norbolethone, which he had synthesized in 1998. About this new venture Arnold recalls "I didn't feel I was jumping into anything more than potential problemwith a sports governing body," and attributes his motivation for involvement to his curiosity about the responsiveness of well-trained athletes, as well as pride in his own work. In 2001 Arnold switched to providing Conte with
tetrahydrogestrinone Tetrahydrogestrinone (THG), known by the nickname The Clear, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It was developed by Patrick Arnold and was used by a number of high-profile ...
after norbolethone started to draw scrutiny from drug testers. Arnold has a chapter giving advice in
Tim Ferriss Timothy Ferriss (born July 20, 1977) is an American entrepreneur, investor, author, podcaster, and lifestyle guru. He became well-known through his ''4-Hour'' self-help book series—including ''The 4-Hour Work Week'', ''The 4-Hour Body'', and '' ...
' book
Tools of Titans ''Tools of Titans: The Tactics, Routines, and Habits of Billionaires, Icons, and World-Class Performers'' (2016) is a self-help book by Timothy Ferriss, an American writer, educational activist, and entrepreneur. He interviewed more than 100 "wor ...
.


Time in prison

In 2006, Arnold was sentenced to three months in prison at
Federal Correctional Institution, Morgantown The Federal Correctional Institution, Morgantown (FCI Morgantown) is a minimum-security United States federal prison for male inmates in West Virginia. It is operated by the Federal Bureau of Prisons, a division of the United States Department of ...
in
West Virginia West Virginia is a state in the Appalachian, Mid-Atlantic and Southeastern regions of the United States.The Census Bureau and the Association of American Geographers classify West Virginia as part of the Southern United States while the B ...
followed by three months of house arrest for his role in the
BALCO scandal The BALCO scandal was a scandal involving the use of banned, performance-enhancing substances by professional athletes. The Bay Area Laboratory Co-operative (BALCO) was a San Francisco Bay Area business which supplied anabolic steroids to profes ...
.


References


External links


Official blog
{{DEFAULTSORT:Arnold, Patrick Living people University of New Haven alumni 21st-century American chemists People from Guilford, Connecticut Date of birth missing (living people) American people convicted of drug offenses 1966 births